In the world of cannabinoids, it can be easy to get confused by all the major players: THC, CBD, CBN, THCA, CBG, THCV, etc. CBDA vs CBD seems like a debate over one letter, but the compounds may have profound differences for medical treatments.
CBD has been around for quite a while now and new products like CBDA hemp oil are popping up on the market. This guide will show you the difference between both cannabinoids, how they are similar, and how they are used.
What Is CBDA?
Cannabidiolic acid, or CBDA, is one of the many naturally occurring cannabinoids on cannabis plants. It is the precursor to CBD. Very little CBD is found on living marijuana plants. Instead, CBDA is rich in the raw form of cannabis.
The benefits of CBDA may look eerily similar to CBD from the outside. This makes sense since we know that CBD is the derivative of CBDA after decarboxylation. CBDA is effective in treating inflammation, nausea, and anxiety.
Unlike CBD, research hasn’t proven many effects of using CBDA in humans. The research on this compound is still in its infancy. But it does show promise for inflammation, nausea, and anxiety in humans.
The molecular structure of CBDA is similar to NSAID drugs, like Aspiring and Acetometaphine. Research also shows that it has the same inflammation reduction effects of NSAIDs by inhibiting COX-2 activity.
For nausea and anxiety, it has been directly compared to CBD and it has shown to have 1,000 times the affinity to bind to the serotonin receptors responsible for controlling nausea and anxiety.
While research hasn’t been able to repeat this yet, it’s clear that CBDA may be the medicinal cannabinoid of choice in the future!
What Is CBD?
Cannabidiol, or CBD, is the active form of CBDA. It is the most researched non-psychoactive cannabinoid and is used medicinally for many ailments. It has been researched quite a bit over the last couple of decades and shows a lot of promise.
CBD also acts as a regulator of THC and its effects. CBD is widely used for its medicinal purposes and lack of psychoactive effects, unlike THC. There is some evidence that CBD and THC work together to create a more effective medicinal treatment for many conditions.
CBD has been studied a lot more than CBDA, so more data is showing its promise. It is used to treat epilepsy, inflammation, and anxiety.
Its neuroprotective properties show promise for treating conditions like epilepsy and multiple sclerosis. However, this is another area that shows better results when it is combined with THC.
While there are many approved medications to treat depression and anxiety, many of them can have serious side effects. CBD is effective at reducing the occurrence of depression and anxiety in users. The best thing about it is the lack of side effects that CBD has compared to other prescription drugs.
It also has promise in improving heart health, reducing the risk for tumor development, and treating symptoms of cancer.
Even though it has been studied more than CBDA, more research is still needed to create more effective medicinal treatments using CBD, or any combination of cannabinoids.
What Is The Difference Between CBD And CBDA?
Then, the cannabis is harvested and the decarboxylation process begins. Drying and curing plant material will start to slowly convert CBDA to CBD. Exposure to room temperature and UV light can also activate the process.
CBDA is immediately turned into CBD when it is exposed to high heat, like smoking.
To be able to ensure that CBDA is present in the end product, temperatures must be low and extractions must be made with raw cannabis material. Then, the end product must be stored in optimal conditions and not heated to avoid turning into CBD right before consumption.
CBDA doesn’t interact with the endocannabinoid system as CBD does. That’s why it’s considered the inactive form of CBD. However, research is showing that CBDA still has potential for medicinal treatments just like CBD, even if it doesn’t act upon the endocannabinoid receptors the same way that CBD does.
CBD & CBDA Products
There is a myriad of CBD products on the market today. It is even sold in places where marijuana is still illegal. CBDA oil is newer and harder to find. A CBDA tincture must be processed and stored correctly to even contain CBDA at all.
There are also CBDA edibles, as long as the food wasn’t cooked at high temperatures. Juicing raw cannabis is a popular choice for those looking to consume CBDA.
Pretty much anything that doesn’t involve smoking CBDA is good to go since this will convert it directly to CBD.
Does CBDA make you high like THC?
CBDA Vs CBD – Which Is Right For You?
When looking to use CBD or CBDA, using a blend may be the most potent to ensure you reap all the possible benefits. The CBDA vs CBD debate will continue to rage on for years to come as cannabis becomes legal in new places and more researchers put the compounds to the test. For now, you can enjoy CBD or CBDA syrup and find out the benefits for yourself!